General overview of Depression study procedures

Interview

Participants will undergo a clinical interview and complete questionnaires, providing background on mood, behavior, and history. While the interview may last anywhere from one to four hours, the questionnaires are available to complete at home.

fMRI Procedures

FMRI data collection requires approximately 1½-2 hours, with nearly 1 hour spent inside the MR scanner. Inside the scanner, subjects will complete computer-based tasks, allowing us to investigate the function of brain regions involved in various cognitive skills. Following the scan, participants are debriefed and allowed to ask any additional questions.

Genetic Testing

In order to investigate the relationship between genes and brain function, subjects will either have saliva or blood sample collected. They will not be used for diagnostic purposes, and all information obtained through the study will remain confidential. The main purpose of collecting this information and DNA is to identify genes influencing psychiatric disorders, other behaviors, and other characteristics of brain structure and function.