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Clinical Neuroscience and Develo

Clinical Neuroscience and Development Laboratory

Research - Current Projects

ADHD
"Characterizing Two Distinct ADHD Neurobiologies with fMRI"
A study that examines brain activity, performance on tests of attention or similar mental abilities, and genetic markers to determine whether symptoms of ADHD are related to different biological causes.  Please visit this website for more information:
www.harthosp.org/adhd

Depression
"
Measuring Differences in Brain Activity in Adolescents with Major Depressive Disorder (MDD) using fMRI"
This study uses fMRI to investigate whether brain function is related to depression symptoms and behavior in teens 11-19 who are currently diagnosed with MDD and have had a previous suicide attempt.

Typical Development
"
Adolescent Maturation of Brain Network Integration for Executive Control Abilities"
This study examines executive functioning as it relates to brain development in healthy adolescents and young adults, ages 12-24. Cognition and behavioral control are studied using paper and pencil tasks, computer tasks, and an fMRI scan, during which participants will be engaged in computer tasks.

For more information, please call Emily at (860)545-7545 or Devra at (860)545-7363.

Autism Spectrum Disorders
"
Language Functioning in Optimal Outcome Children with a History of Autism"
In collaboration with the University of Connecticut, this study examines brain activity as it relates to language function and facial recognition in
children who maintain their Autistic Spectrum Disorder (ASD) diagnoses over time, Optimal Outcome children who were once diagnosed with ASD but no longer meet criteria for a diagnosis of ASD, and typically developing children.

Neurocognitive Development
There is a strong focus in the lab on projects that will ultimately help us better understand neural differences between younger and older groups, particularly neural development that occurs after puberty into early adult years. Numerous studies of brain structure, brain function, and cognitive test performance show developmental changes throughout this critical period of transition between childhood and adulthood. However, there is insufficient understanding of how changes in cognition and behavioral control relate to these neurobiological factors.

Multimodal Data Fusion is the process of combining data obtained from different modalities (e.g., fMRI and EEG) and integrating them in the same analytic framework. Such analyses are extremely powerful ways to maximize the usefulness of obtained datsets, as each research methodology carries its own set of strengths and limitations. By capitalizing on the qualitatively different types of information provided by each modality, it is possible to approach old questions in new ways.

 

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