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The People of the Olin Neuropsychiatry Research Center

The People of the Olin Neuropsychiatry Research Center

Michal Assaf, M.D.
Senior Research Scientist
Institute of Living at Hartford Hospital

Assistant Professor Adjunct
Department of Psychiatry

Yale University School of Medicine

200 Retreat Avenue
Whitehall Building - Institute of Living
Hartford CT 06106
Phone: 860-545-7700, ext 7792
Email: massaf@harthosp.org

Who Am I?

Dr. Michal Assaf has studied mental illnesses by implementing cognitive neuroscience and neuroimaging concepts. She earned her M.D. in 2001 at Tel Aviv University following a clinical internship at the Edith Wolfson Hospital in Israel.

Dr. Assaf completed a two-year postdoctoral fellowship at the Division of Psychiatric Neuroimaging of the Johns Hopkins University School of Medicine. In 2003 she joined the Olin Neuropsychiatry Research Center at the Institute of Living as a Postdoctoral Associate of the Yale School of Medicine.

Dr. Assaf was jointly appointed as a Senior Research Scientist at the Institute of Living and Assistant Professor Adjunct at Yale University, and has been researching neuropsychiatric disorders while focusing on three major projects:

  • Social Cognition, focusing on different brain mechanisms involved in social cognition and their association with various psychiatric disorders, such as autism spectrum disorders, schizophrenia and substance abuse. Dr. Assaf has implemented an fMRI paradigm of a modified domino game that entails decision making and risk-taking behavior under conditions of uncertainty.

  • Semantic Memory, concentrating on feature binding abnormalities in schizophrenia and bipolar disorder, and the relationship between semantic processing and formal-thought disorder.

  • Resting state brain activity and functional connectivity. Using advance analytical techniques, such as independent component analysis (ICA) and functional network connectivity (FNC), of fMRI and PET data, Dr. Assaf has investigated the “default-mode” sub-networks in patients with autism spectrum disorders, amnesic mild cognitive impairment (MCI) and early Alzheimer’s Disease (AD).

Dr. Assaf is a licensed physician in Israel and a member of The International Society for Autism Research (INSAR) and The Society for Neuroscience

Publications

Assaf M, Rivkin P, Kuzu C, Calhoun V, Kraut M, Groth K, Yassa M, Hart J and Pearlson GD (2006). Abnormal Object-Recall and Anterior Cingulate Overactivation Correlate with Formal Thought Disorder in Schizophrenia. Biol Psychiatry, 59(5): 452-9.

Assaf M, Calhoun V, Kuzu C, Kraut M, Rivkin P, Hart J and Pearlson GD (2006). Neural Correlates of the Object Recall Process in Semantic Memory. Psychiatry Research: Neuroimaging, 147 (2-3): 115-126.

Assaf M, Kahn I, Pearlson GD, Johnson MR, Yeshurun Y, Calhoun V and Hendler T (2009). Brain Activity Dissociates Mentalization from Motivation during an Interpersonal Competitive Game. Brain Imaging and Behavior, 3 (1): 24-37.

Assaf M, Jagannathan K, Calhoun V, Kraut M, Hart J and Pearlson G. (2009) Temporal Sequence of Hemispheric Network Activation during Semantic Processing: A Functional Network Connectivity Analysis. Brain and Cognition, 70 (2): 238-246.

Book Chapter

Assaf M, Rivkin P, Kraut M, Calhoun V, Hart J and Pearlson G (2007). Schizophrenia and Semantic Memory. In Hart J and Kraut M. Neural Basis of Semantic Memory. Cambridge University Press, Cambridge, UK.
 

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