The People of the Olin Neuropsychiatry Research Center

Michael C. Stevens, Ph.D Director Clinical Neuroscience and Development Laboratory Olin Neuropsychiatry Research Center Director, Child & Adolescent Research Hartford Hospital/The Institute of Living Assistant Professor Department of Psychiatry Yale University School of Medicine 200 Retreat Avenue Whitehall Building - Institute of Living Hartford CT 06106 Phone: 860-545-7700, ext 7552 Email: msteven@harthosp.org

Who Am I?

Dr. Michael C. Stevens directs two complementary programs of research. He leads the Clinical Neuroscience and Development Laboratory (LINK), which uses neuroscience research techniques to understand the neurobiological substrates of psychiatric illnesses that develop in childhood and adolescence. He also is the director of Child and Adolescent Research for The Institute of Living at Hartford Hospital. In this role, Dr. Michael C. Stevens is responsible for overseeing and contributing to all pediatric psychiatric research at the Institute.

Roles and Responsibilities include:

• Lead the Clinical Neuroscience and Development Laboratory

• Lead the Child and Adolescent Research for the Institute of Living

Objectives/Interests in Neuropsychiatry:

• Developmental psychopathology and clinical neuroscience, especially disruptive behavior disorders of childhood and adolescence and their adult sequelae.

• Identifying functionally-integrated neural systems in the brain and determining how normal and pathological development influence how ensembles of brain regions interact to form the substrates of cognition and behavior.

• Changes in neural correlates of cognitive development across the lifespan to help refine neurobiological models of cognitive development.

• The neurobiological basis for disrupted attention and executive-functions in psychiatric disorders.

Current Projects:

• A study of psychostimulant medication in AD/HD adolescents and adults using fMRI, EEG, and neuropsychological assessment.
• Neurocognitive Correlates of Disruptive Behavior Disorders, a 5-year NIMH funded study of AD/HD and Conduct Disorder using fMRI, EEG, and neuropsychological assessment.
• Diffusion Tensor Imaging study of mild head injury, relationships with post-injury cognitive and psychosocial impairment.
• A study of the effect of structured cognitive therapy for adolescent girls with PTSD on brain function measured by fMRI.
• Neurobiological factors contributing to impulsive suicidality in adolescents with major depressive disorders.
• Different impulsivity phenotypes in Attention-Deficit/Hyperactivity Disorder, a combined fMRI and genetic inquiry.
• A study of intramuscular olanzapine in the management of acute agitation in pediatric residential psychiatric care.

Dr. Stevens' current CV

Publications

Fein, D., Stevens, M.C., Dunn, M., Waterhouse, L., Allen, M., Rapin, I., & Feinstein, C. (1999). Subtypes of pervasive developmental disorder: Clinical characteristics. Child Neuropsychology, 5(1): 1-23.

Stevens, M.C., & Fein, D., Waterhouse, L.H. (2000). Season of birth effects in autism. Journal of Clinical and Experimental Neuropsychology, 22(3): 399-407.

Stevens, M.C., Fein, D., Dunn, M., Allen, D., Waterhouse, L. H., Feinstein, C. & Rapin, I. (2000). Subgroups of children with autism by cluster analysis: A longitudinal examination. Journal of the American Academy of Child and Adolescent Psychiatry, 39(3): 346-352

Stevens, M.C. Fein, D.A. & Markus, E. (2001). Connecticut Pictorial Learning Test: A pictorial version of the California Verbal Learning Test. Clinical Neuropsychologist 15(1): 95-108.

Stevens, M.C., Kaplan, R.F. & Bauer, L.O. (2001). Relationship of cognitive ability to the developmental course of antisocial behavior in substance-dependent patients. Progress in Neuro-Psychopharmacology & Biological Psychiatry 25(8): 1523-1536.

Kaplan, R.F. & Stevens, M.C. (2002). A review of adult Attention Deficit/Hyperactivity Disorder: A neuropsychological and neuroimaging perspective. CNS Spectrums, 7(5): 355-362.

Stevens, M.C., Kaplan, R.F. & Hesselbrock, V.M. (2003). Executive cognitive functioning in the development of antisocial personality disorder. Addictive Behaviors, 28: 285-300

Taxel, P., Stevens, M.C., Trahiotis, M., Zimmerman, J., & Kaplan, R.F. (2004). The effect of short-term estradiol therapy on cognitive function in men receiving hormonal suppression therapy for treatment of prostate cancer. American Journal of Geriatric Psychiatry, 52(2): 269-273.

Calhoun, V.D., Stevens, M.C., Pearlson, G., & Kiehl, K.A. (2004). fMRI analysis with the General Linear Model: Removal of latency-bias by using hemodynamic derivative terms. Neuroimage, 22: 252-257.

Kiehl, K. A., Stevens, M.C., Laurens, K.R., Pearlson, G.D., & ., Liddle, P.F. (2005) An adaptive reflexive processing model of neurocognitive function: supporting evidence from a large scale (n = 100) fMRI study of an auditory oddball task. Neuroimage, 25(3): 899-915.

Calhoun, V.D., Adali, T, Stevens, M.C., Kiehl, K.A. & Pekar, J (2005). Semi-blind ICA of fMRI: A method for utilizing hypothesis-derived time courses in a spatial ICA analysis. NeuroImage, 25(2): 527-38.

Kiehl, K. A., Stevens, M. C., Celone, K., Kurtz, M. & Krystal, J.H. (2005). Abnormal hemodynamics in schizophrenia during an auditory oddball task. Biological Psychiatry, 57(9): 1029-40.

Stevens, M.C., Calhoun, V.D., & Kiehl, K.A. (2005). Hemispheric differences in hemodynamics elicited by auditory oddball stimuli. NeuroImage, 26(3): 782-92.

Stevens, M.C., Clark, V.P., Prestwood, K. (2005). Low-dose estradiol alters brain activity. Psychiatry Research: Neuroimaging, 139(3): 199-217.

Mandelbaum DE, Stevens M.C., Rosenberg E, Wiznitzer M, Steinschneider M, Filipek P, Rapin I. (2006) Comparison of sensory/motor performance in school-age children with autism, developmental language disorder or low IQ. Dev Med Child Neurol. 48(1):33-39.

Stevens M.C., Calhoun V.D., Kiehl K.A. (2005). fMRI in an oddball task: Effects of target-to-target interval. Psychophysiology. 42(6):636-642.

Stevens M.C. (2005). Functional neuroimaging in child and adolescent psychiatry. Conn Med. 69(9):561-570.

Astur, R.S., St. Germain, S., Tolin, D., Ford, J., Russell, D., Stevens, M.C. (2006). Hippocampus function predicts severity of post-traumatic stress disorder. CyberPsychology & Behavior, 9, 234-239.

Stevens, M.C., Laurens, K.R., Liddle, P.F. & Kiehl, K.A. (2006) The hemodynamics of oddball processing during single-tone and two-tone target detection tasks. Int J Psychophysiol 60, 292-303.

Stevens, M.C., Kiehl, K.A., Pearlson, G., Calhoun V.D. (in press) Functional neural circuits for mental timekeeping. Human Brain Mapping.

Stevens, M. C., Kiehl, K. A., Pearlson, G. D., & Calhoun, V. D. (2007). Functional neural networks underlying response inhibition in adolescents and adults. Behav Brain Res, 181(1), 12-22.

Stevens, M. C., Pearlson, G. D. & Kiehl, K. A. (2007). An fMRI Auditory Oddball Study of Combined-Subtype Attention-Deficit/Hyperactivity Disorder. Am J Psychiatr. 164, 1-13.

Stevens, M. C., Kiehl, K. A., Pearlson, G. D., & Calhoun, V. D. (2007). Brain network dynamics during error commission. Human Brain Mapping. Published online, Nov 2, 2007
 

Jafri, M., Stevens, M.C., Pearlson, G., Calhoun, V.D. (2008). A Method for functional network connectivity among spatially independent resting-state components in schizophrenia. Neuroimage, 39(4), 1666-81.