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Shashwath Meda
Imaging Analyst
Olin Neuropsychiatry Research Center
200 Retreat Avenue
Whitehall Building - Institute of Living
Hartford CT 06106
Phone: 860-545-7700, ext 7804
Email: smeda01@harthosp.org |
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Shashwath's
CV
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Who Am I?
Shashwath Meda completed his Bachelor of Engineering in Electrical and
Electronics from India. Following his Bachelors he obtained an advanced
degree in Biomedical Engineering from Wayne State University (Michigan) in
2005. During his graduate career, he was part of the MR Research Facility
(Detroit Medical Center) involved in active research on presurgical
functional mapping and development of novel MR biomarkers for TBI (Traumatic
Brain Injury), under the dual mentorship of Dr. E. Mark Haacke and Dr.
Randall. R. Benson.
Early 2006 he joined The Olin Neuropsychiatry Research Center and currently
holds the position of a senior clinical data analyst. As part of his job he
serves as a liaison between PI’s and multiple projects involving complex
data/imaging analysis. His major interests include 1) Assessing
genotype-phenotype relationships using univariate and multivariate imaging
techniques in psychiatric populations 2) Connectivity analysis in cohorts
with major neuropathology 3) Exploring brain function and morphology in
substance abuse groups.Currently
Active Projects
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Identifying
the role of genes on brain function and morphology in healthy, substance
abuse and other psychiatric illnesses.
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Influence of alcohol on driving - Investigating the functional brain
circuitry and localization using ICA and SPM.
Grants
Harford Hospital New investigator grant - Characterizing the Dyslexia
Phenotype using Genetics and MR Morphology
Role: Primary Investigator
Publications
Meda S.A.,
Stevens
M.C., Potenza M.D., Pittman B., Gueorguieva R., Andrews M.M., Thomas
A.D., Muska C., Hylton J.L & Pearlson G.D. (2009) Investigating the
Behavioral and Self-Report Constructs of Impulsivity Domains using Principal
Component Analysis. Behavioral Pharmacology-In Press
Allen, A. J.,
Meda, S. A., Skudlarski, P., Calhoun, V. D., Astur, R. S., Ruopp,
K., & Pearlson, G. D. (2009) Effects of alcohol on performance on a
distraction task during simulated driving. Alcohol Clin Exp Research,
33(4):617-25.
Meda, S. A.,
Bhattarai, M., Morris, N. A., Astur, R. S., Calhoun, V. D., Mathalon, D. H.,
Kiehl, K. A., & Pearlson G. D. (2008). An fMRI study of working memory in
first-degree unaffected relatives of schizophrenia patients. Schizophr
Res, 104(1-3), 85-95.
Meda, S. A.,
Calhoun, V. D., Astur, R. S., Turner, B. M., Ruopp, K., & Pearlson, G. D.
(2008). Alcohol dose effects on brain circuits during simulated driving: An
fMRI study. Hum Brain Mapp., 30(4): 1257-70.
Meda, S. A.,
Giuliani, N. R., Calhoun, V. D., Jagannathan, K., Schretlen, D. J., Pulver,
A., Cascella, N., Keshavan, M., Kates, W., Buchanan, R., Sharma, T., &
Pearlson, G. D. (2008). A large scale (N=400) investigation of gray matter
differences in schizophrenia using optimized voxel-based morphometry.
Schizophr Res, 101(1-3), 95-105.
Meda, S.A.,
Gelernter, G., Gruen, J.G., Calhoun, V. D., Meng, H., Cope, N.A & Pearlson,
G. D (2008). Polymorphism of DCDC2 reveals differences in cortical
morphology of healthy individuals. Brain Imaging and Behav, 2, 21-26.
Skelly, L. R.,
Calhoun, V., Meda, S. A., Kim, J., Mathalon, D. H., & Pearlson,
G. D. (2008). Diffusion tensor imaging in schizophrenia: relationship to
symptoms. Schizophr Res, 98(1-3), 157-162.
Benson, R. R.,
Meda, S. A., Vasudevan, S., Kou, Z., Govindarajan, K. A., Hanks,
R. A., Mills, S. R., Makki, M., Latif, Z., Coplin, W., Meythaler, J., &
Haacke, E. M. (2007). Global white matter analysis of diffusion tensor
images is predictive of injury severity in traumatic brain injury. J
Neurotrauma, 24(3), 446-459.
Meda, S. A.,
Stevens, M. C., Folley, B. S., Calhoun, & Pearlson, G. D. Evidence for
anomalous network connectivity during working memory in schizophrenia (Under
Review – Schizophrenia Research)
Parker, B. A.,
Thompson, P. D., Ruopp, K. C., Meda, S. A., Grimaldi, A. S., &
Pearlson, G. D. Exercise training alters hippocampal activity and function
in humans (Under Review – Medicine and science in sports and exercise)
Andrews M.M.,
Meda S.A., Thomas A.D., Potenza M.D., Krystal J.H., Worhunsky P.,
Stevens M.C., O’ Malley S., Book G., & Pearlson G.D. Individuals Family
History Positive for Alcoholism Show fMRI Abnormalities in Reward
Sensitivity, Related to Impulsivity Factors (Under Review – Archives of
General Psychiatry)
Rzepecki C.I.,
Meda S.A., Calhoun V.D., Stevens M.C., Jafri M.J., Astur R.S., &
Pearlson G.D. Disruptions in Functional Neural Connectivity During Drunk
Driving. (Under Review –
Alcohol Clinical
Experimental Research)
Lui S., Li T.,
Deng W., Jiang L., Wu Q., Tang H., Yue Q., Wei Y., Huang X., Collier D.A.,
Meda S.A., Pearlson G.D., Mechelli A., Sweeney J.A., & Gong Q.
Short-term effect of antipsychotic treatment on cerebral function in
drug-naïve first episode schizophrenia revealed by rfMRI at 3T. (Under
Review – Nature Neuroscience)
Parker, B. A.,
Thompson, P. D., Ruopp, K. C., Meda, S. A., Grimaldi, A. S., &
Pearlson, G. D. Changes in memory function and neuronal activation
associated with atorvastatin therapy (Under Review – Pharmacotherapy)
Meda, S. A.,
Jagannathan K., Gelernter, J., Calhoun V.D., Liu J.,Stevens, M. C., &
Pearlson, G. D. A pilot multivariate parallel ICA study to investigate
differential linkage between neural networks and genetic profiles in
schziophrenia (Under Review – Neuroimage)