The People of the Olin Neuropsychiatry Research Center

Who Am I?

I am interested in medical imaging. Our group does quantitative neuro-imaging as a means to learn more about psychiatric conditions…in particular, Schizophrenia, Alzheimer's Disease, Down Syndrome. Also we are involved in a large study investigating aging and cognition. I have a particular interest in MRI since I believe it has a large amount of information to offer about the human condition. Other areas I enjoy are the merging together of information from various imaging modalities and even other sources from both a systems viewpoint and a software development viewpoint (e.g. PACS systems, Image Analysis and Visualization Software Packages).

Roles and Responsibilities:

• Directing the medical image analysis lab
• Development of image analysis methods
• Research planning and implementation in functional MRI
• Development of structural and functional image analysis software (image processing, filtering, segmentation, etc.)
  

Objectives/Interests in Neuropsychiatry:

• To develop methods/software for improving visualization of structure and function in medical images.
• To study the brain in healthy controls and in patients with mental disease in order to increase understanding and promote health.
  

Current Projects:

• Development of processing methods for functional MRI
• Development of functional MRI projects (latency mapping, independent components analysis, adaptive filtering)
• Co-development of Java cross-platform medical imaging visualization (blox) and analysis package (functional analysis components)

Honors and Professional Memberships:

• Tau Beta Pi (President)
• Mortar Board (Treasurer)
• Phi Beta Kappa
• 1991-present IEEE Member, ISMRM Member
• 1996-present AAAS Member

Publications:

• V.Calhoun, T.Adali, G.Pearlson, and J.Pekar, A Method for Making Group Inferences From Functional MRI Data Using Independent Component Analysis Hum.Brain Map., vol. 14, pp. 140-151, 2001.
• V.Calhoun, T.Adali, V.McGinty, J.Pekar, T.Watson, and G.Pearlson, FMRI Activation In A Visual-Perception Task: Network Of Areas Detected Using The General Linear Model And Independent Components Analysis NeuroImage, 2001.
• V.Calhoun, T.Adali, G.Pearlson, and J.Pekar, Group ICA of Functional MRI Data: Separability, Stationarity, and Inference Proceedings, ICA2001, San Diego, CA, 2001.
• V.Calhoun, T.Adali, and G.Pearlson, Independent Components Analysis Applied To fMRI Data: A Generative Model for Validating Results Proceedings, NNSP, Falmouth, MA, 2001.
• V.D.Calhoun, T.Adali, G.D.Pearlson, and J.J.Pekar, Spatial and Temporal Independent Component Analysis of Functional MRI Data Containing a Pair of Task-Related Waveforms Hum.Brain Map., vol. 13, pp. 43-53, 2001.
• V.Calhoun, V.McGinty, J.Pekar, T.Watson, and G.Pearlson, Investigation of Marinol (THC) Effects upon fMRI Activation During Active and Passive Driving Using Independent Component Analysis and SPM NeuroImage, vol. 13, no. 6, p. S388, 2001.
• V.Calhoun, J.Pekar, T.Adali, and G.Pearlson, fMRI Of Visual Perception: Networks Identified By SPM And Independent Component Analysis Proceedings, ISMRM, 10th Annual Meeting, Glasgow, Scotland, p. 1742, 2001.
• V.Calhoun, T.Adali, and G.Pearlson, Independent Components Analysis Applied To fMRI Data: A Natural Model And Order Selection Proceedings, NSIP, Baltimore, 2001.
• V.Calhoun, T.Adali, G.Pearlson, and J.Pekar, A Method for Making Group Inferences Using Independent Component Analysis of Functional MRI Data: Exploring the Visual System NeuroImage, vol. 13, no. 6, p. S88, 2001.
• V.Calhoun, J.Pekar, T.Adali, and G.Pearlson, An fMRI Analysis of Driving-Related Networks with Independent Component Analysis Applied in a Between-Condition (BC-ICA) and Within-Condition (WC-ICA) Manner Proceedings, ISMRM, 10th Annual Meeting, Glasgow, Scotland, p. 668, 2001.
• J.Pekar, V.Calhoun, T.Adali, and G.Pearlson, Spatial & Temporal Independent Component Analysis of fMRI Data with Two Task-Related Waveforms Proceedings, ISMRM, 10th Annual Meeting, Glasgow, Scotland, p. 24, 2001.
• A.Horska, V.Calhoun, and P.B.Barker, A Rapid Method for Correction of CSF Partial Volume in Quantitative Proton MR Spectroscopic Imaging Proceedings, ISMRM, 10th Annual Meeting, Glasgow, Scotland, p. 216, 2001.
• M.A.Kraut, S.Kremen, L.Moo, J.B.Segal, V.Calhoun, and J.Hart, Object Activation From Features in the Semantic System J.Cogn Neurosci., 2001.(In Press)
• M.A.Kraut, S.Kremen, J.B.Segal, V.Calhoun, L.Moo, and J.Hart, Object Activation in Semantic Memory From Visual Multimodal Feature Input J.Cogn Neurosci., 2001.(In Press)
• S.Mostofsky, M.Abrams, S.Arnold, Y.Choe, V.Calhoun, and J.Pekar, Functional MRI Examination of Motor Response Inhibition Proceedings, INS, 2001.
• K.O.Yates, H.M.Morris, H.Strasser, N.A.Honeycutt, D.Schretlen, P.Barta, J.Anthony, V.Calhoun, and G.Pearlson, Linear Regression Model Based on Age- and Sex-Related Increase in MRI Volumes of Ventricles Proceedings, SBP, 2001.
• V.Calhoun, T.Adali, M.Kraut, and G.Pearlson, A Weighted-Least Squares Algorithm for Estimation and Visualization of Relative Latencies in Event-Related Functional MRI Mag.Res.Med., vol. 44, pp. 947-954, 2000.
• V.Calhoun and G.Pearlson, The brain as a black-box?: ER-fMRI latency estimation of interleaved responses to short visual, auditory, and motor stimuli Proceedings, ISMRM, 9th Annual Meeting, Denver, CO, p. 983, 2000.
• V.Calhoun, M.Kraut, T.Adali, and G.Pearlson, A Weighted-Least Squares method for latency estimation in fMRI Proceedings, ISMRM, 9th Annual Meeting, Denver, CO, p. 814, 2000.
• V.Calhoun, X.Golay, and G.Pearlson, Improved fMRI Slice Timing Correction: Interpolation Errors and Wrap Around Effects Proceedings, ISMRM, 9th Annual Meeting, Denver, CO, p. 810, 2000.
• V.Calhoun, V.McGinty, T.Watson, and G.Pearlson, Insights Into Functional Connectivity During A Driving Simulation Before And After Effects Of Marinol Intoxication On FMRI Activation And Cognitive Performance Proceedings, ACNP, 39th Annual Meeting, Puerto Rico, 2000.
• V.Calhoun and J.Pekar, Where and Where Are Components Independent? On the Applicability of Spatial- and Temporal- ICA to Functional MRI Data NeuroImage, vol. 11, p. S682, 2000.
• S.Nicastri, V.Calhoun, G.Pearlson, C.A.Buchpiguel, A.S.Tanaka, M.C.eite, and A.G.ndrade, Cortical Blood Flow Abnormalities in Cocaine-Dependent Individuals Evaluated by Single Photon Emission Computed Tomography: A Method of Quantification Proceedings, CPDD, 2000.
• G.D.Pearlson, V.D.Calhoun, M.Grygorcewicz, T.E.Schlaepfer, S.Nicastri, M.Stephane, A.Marusic, S.Dogan, D.Wong, and A.A.Harrison, Effects of Oral Delta 9-Tetrahydrocannabinol (THC), (Marinol) on Time Estimation, Subjective Intoxication and PET Measures of Regional Cerebral Bloodflow Neuropsychopharmacology., 2000.
• V.Calhoun, T.Adali, and G.Pearlson, Adaptive Filtering Of Visual Evoked Responses In fMRI: Variability Of Response Proceedings, IASTED-SIP, Nassau, Bahamas, 1999.
• V.Calhoun, T.Adali, and G.Pearlson, (Non)Stationarity Of Temporal Dynamics In fMRI Proceedings, EMBS/BMES Joint Meeting, Atlanta, GA, 1999.
• M.Kraut, V.Calhoun, and A.Mandir, Regional Segragation of Task-Timing Related Activation in Human Supplementary Motor Area, Studies by fMRI Proceedings, Soc.of Neuroscience, New Orleans, LA , 1999.
• M.Kraut, V.Calhoun, A.Mandir, L.Marsh, and G.Pearlson, FMRI of Task-Timing Related Activation Patterns in the Human Supplementary Motor Area Proceedings, RSNA, 85th Annual Meeting, Chicago, IL, 1999.
• S.Nicastri, V.Calhoun, G.Pearlson, C.A.Buchpiguel, A.S.Tanaka, M.C.Leite, and A.G.Andrade, Cortical Blood Flow Abnormalities in Cocaine-Dependent Individuals Evaluated by Single Photon Emission Computed Tomography: A Method of Quantification Proceedings, NIDA, 1999.
• V.Calhoun, T.Adali, and G.Pearlson, A frequency-space approach for motion correction in fMRI Proceedings, IMDSP, 10th Annual Meeting, Alpbach, Austria, p. 229, 1998.
• V.Calhoun and G.Pearlson, Spatially-Distributed Lag Time Estimation In Event-Related fMRI Via Adaptive Filtering Proceedings, BMES, 1998 Annual Fall Meeting, Atlanta, 1998.
• V.Calhoun, T.Adali, M.Kraut, P.Rivkin, and G.Pearlson, Visualizing Spatially Distributed Hemodynamic Lag Times In Event-Related Functional MRI: Estimation Of A Characteristic Visual "Impulse Response" Proceedings, EMBS, 20th Annual Meeting, Hong Kong, 1998.
• S.Eleff, P.Rivkin, M.Grygorcewicz, V.Calhoun, Y.Chen, B.Chance, and G.D.Pearlson, A novel non-invasive phase modulated near-Infrared Imaging method demonstrates abnormal cortical activation in schizophrenics during cognitive testing. 1998.
• G.Pearlson, V.Calhoun, D.Wong, A.Marusic, M.Grygorcewicz, S.Nicastri, L.Ellison, and T.E.Schlaepfer, The Effects on Cerebral Blood Flow and Time Estimation Proceedings, ACNP, 37th Annual Meeting, Puerto Rico, 1998.
• S.Kalyanasundaram, V.D.Calhoun, and K.W.Leong, A Finite Element Model for Predicting the Distribution of Drugs Delivered Intracranially to the Brain Am.J.Physiol., vol. 273, p. R1810-R1821, 1997.
• B.Reisfeld, S.Blackband, V.Calhoun, S.Grossman, S.Eller, and K.Leong, The Use of Magnetic Resonance Imaging to Track Controlled Drug Release and Transport in the Brain Mag.Res.Imag., vol. 11, pp. 247-252, 1993.